Online Question Bank For
The FRCS General Surgery Exam

Studies

Dutch TME trial - Short term outcomes - Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer [Neoadjuvant SCRT & TME vs Neoadjuvant SCRT & No TME]

Swedish Rectal trial - Improved survival with preoperative radiotherapy in resectable rectal cancer [Neoadjuvant SCRT & No TME vs No SCRT & No TME]

German Rectal trial - Long term outcomes: Preoperative versus postoperative chemoradiotherapy for rectal cancer [Neoadjuvant LCRT & TME vs TME & Adjuvant LCRT]

German Rectal trial - Longer term outcomes: Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years [Neoadjuvant LCRT & TME vs TME & Adjuvant LCRT]

Rapido trial - Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial. [LCRT, TME & Adjuvant Chemotherapy vs LCRT, TME & No Adjuvant Chemotherapy]

Rapido trial subgroup analysis -The value of post-operative chemotherapy after chemoradiotherapy in patients with high-risk locally advanced rectal cancer-results from the RAPIDO trial. [LCRT, TME & Adjuvant Chemotherapy vs LCRT, TME & No Adjuvant Chemotherapy]

PRODIGE trial - Long term outcomes - Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial. [Total neodjuvant Rx - Induction Chemo , LCRT, TME +- Adj Chemotherapy(clinician choice) vs LCRT, TME +- Adj Chemotherapy(clinician choice)]

PRODIGE trial - Longer term outcomes - Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiation in patients with locally advanced rectal cancer: 7-year results of PRODIGE 23 phase III trial, a UNICANCER GI trial. [Total neodjuvant Rx - Induction Chemo , LCRT, TME +- Adj Chemotherapy(clinician choice) vs LCRT, TME +- Adj Chemotherapy(clinician choice)]

Barcelona trial - Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial.

Barcelona trial: long term results - The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer.

COST trial (Clinical Outcomes of Surgical Therapy Study Group) - A comparison of laparoscopically assisted and open colectomy for colon cancer

MRC CLASICC trial: long term results - Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer

MRC CLASICC trial: longer term results - Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer.

COLOR trial - COlon cancer Laparoscopic or Open Resection Study Group (COLOR). Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial

COLOR trial: long term results - Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial.

COLOR trial: longer term results - ; COLOR (COlon cancer Laparoscopic or Open Resection) Study Group. Ten-year outcomes of a randomised trial of laparoscopic versus open surgery for colon cancer. 

ALCCaS trial - Short-term outcomes of the Australasian randomized clinical study comparing laparoscopic and conventional open surgical treatments for colon cancer: the ALCCaS trial. 

ALCCaS trial: long term results - Long-term outcomes of the australasian randomized clinical trial comparing laparoscopic and conventional open surgical treatments for colon cancer: the Australasian Laparoscopic Colon Cancer Study trial.

MRC CLASICC trial: long term results - Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer

MRC CLASICC trial: longer term results - Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer.

COLOR II trial - COlorectal cancer Laparoscopic or Open Resection II (COLOR II) Study Group. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. 

COLOR II trial: long term outcomes - A randomized trial of laparoscopic versus open surgery for rectal cancer. 

COLOR II trial: QOL - Patient-reported genitourinary dysfunction after laparoscopic and open rectal cancer surgery in a randomized trial (COLOR II). 

COREAN trial - Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial. 

COREAN trial: long term outcomes - . Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial

ACOSOG Z6051 trial - Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes: The ACOSOG Z6051 Randomized Clinical Trial. 

ACOSOG Z6051 trial: long term outcomes - Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer: follow-up results of the ACOSOG Z6051 randomized controlled trial. 

ALaCaRT trial - . Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial. 

ALaCaRT trial: long term outcomes - Disease-free survival and local recurrence after laparoscopic-assisted resection or open resection for rectal cancer: the Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial. 

Increasing Incidence of Thyroid Cancer in the United States, 1973–2002

Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A Paradigm Shift to Reduce Overtreatment of Indolent Tumors

Observational Trial for Papillary Thyroid Microcarcinoma in Japanese Patients

Using the American Thyroid Association Risk Stratification System to Refine and Individualize the American Joint Committee on Cancer Eighth Edition Disease-Specific Survival Estimates in Differentiated Thyroid Cancer

An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer

Extent of Surgery for Papillary Thyroid Cancer is Not Associated with Survival: An Analysis of 61,775 Patients

How Many Lymph Nodes are Enough? Assessing the Adequacy of Lymph Node Yield for Papillary Thyroid Cancer

Estimating Risk of Recurrence in Differentiated Thyroid Cancer after Total Thyroidectomy and Radioactive Iodine Remnant Ablation: Using Response to Therapy Variables to Modify the Initial Risk Estimates Predicted by the New American Thyroid Association Staging System

Outcomes of patients with differentiated thyroid carcinoma following initial therapy

Sorafenib in Radioactive Iodine-Refractory, Locally Advanced or Metastatic Differentiated Thyroid Cancer: A Randomised, DoubleBlind, Phase 3 Trial

Dabrafenib and Trametinib Treatment in Patients with Locally Advanced or Metastatic Braf V600-Mutant Anaplastic Thyroid Cancer

Prophylactic Lateral Neck Dissection for Medullary Thyroid Carcinoma is Not Associated with Improved Survival

Prophylactic Thyroidectomy in Multiple Endocrine Neoplasia Type 2A

Long-Term Outcome in 215 Children and Adolescents with Papillary Thyroid Cancer Treated During 1940 through 2008

Incidence and Prevalence of Primary Hyperparathyroidism in a Racially Mixed Population

A 10-year Prospective Study of Primary Hyperparathyroidism with or without Parathyroid Surgery

Randomized Controlled Clinical Trial of Surgery versus No Surgery in Patients with Mild Asymptomatic Primary Hyperparathyroidism

Operation for Primary Hyperparathyroidism: The New versus the Old Order. A Randomised Controlled Trial of Preoperative Localisation

Operative Failures after Parathyroidectomy for Hyperparathyroidism: The Influence of Surgical Volume

Bilateral Neck Exploration for Sporadic Primary Hyperparathyroidism: Use Patterns in 5,597 Patients Undergoing Parathyroidectomy in the Collaborative Endocrine Surgery Quality Improvement Program

No Need to Abandon Focused Parathyroidectomy: A Multicenter Study of Long-Term Outcome after Surgery for Primary Hyperparathyroidism

Comparison of Intraoperative iPTH Assay (QPTH) Criteria in Guiding Parathyroidectomy: Which Criterion is the Most Accurate?

One Hundred and One Consecutive Transoral Endoscopic Parathyroidectomies via the Vestibular Approach for PHPTH: A Worldwide Multi-Institutional Experience

Cryopreservation of Parathyroid Tissue: An Illustrated Technique Using the Cleveland Clinic Protocol

Intraoperative Parathyroid Autofluorescence Detection in Patients with Primary Hyperparathyroidism

Is Parathyroidectomy Safe and Effective in Patients with Normocalcemic Primary Hyperparathyroidism?

The Phenotype of Primary Hyperparathyroidism with Normal Parathyroid Hormone Levels: How Low Can Parathyroid Hormone Go?

18F-Fluorocholine PET/CT and Parathyroid 4D Computed Tomography for Primary Hyperparathyroidism: The Challenge of Reoperative Patients

Predictors of Operative Failure in Parathyroidectomy for Primary Hyperparathyroidism

Single Gland Excision for Men1-Associated Primary Hyperparathyroidism

Management of the Parathyroid Glands during Preventive Thyroidectomy in Patients with Multiple Endocrine Neoplasia Type 2

Recent Changes in Therapeutic Approaches and Association with Outcomes Among Patients with Secondary Hyperparathyroidism on Chronic Hemodialysis: The Dopps Study

A Randomized Study Comparing Parathyroidectomy with Cinacalcet for Treating Hypercalcemia in Kidney Allograft Recipients with Hyperparathyroidism

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